| Name | Description |
| Acro Bike | A folding bicycle capable of jumps and wheelies. |
| Aguav Berry | When held, 1/8 HP recovers when HP is below half, but Confusion occurs for Pokemon that are Naughty, Lax, Naive, or Rash. |
| Amulet Coin | When held by a Pokemon, double the money is earned from battles. |
| Antidote | Recover from Poison status. |
| Apicot Berry | When held, while in a pinch, Special Defense raises one stage. |
| Aspear Berry | When held, Freeze status recovers by itself. |
| Awakening | Recover from Sleep status. |
| Basement Key | The key for NEW MAUVILLE beneath MAUVILLE CITY. |
| Bead Mail | Mail which shows a sketch of the Pokemon holding it. |
| Belue Berry | Bury in the earth to grow BELUE ingredients for PokéBlocks. |
| Berry Juice | Made completely from berries, it restores 20 HP for a Pokemon. |
| Big Mushroom | A rare mushroom. Sells high. |
| Big Pearl | A very pretty large pearl. Sells high. |
| Black Belt | When held, a Pokemon's Fighting type moves' power increases by 10%. |
| Black Flute | Play this glass flute to encounter wild Pokemon less often. |
| Blackglasses | When held, a Pokemon's Dark type moves' power increases by 10%. |
| Blue Flute | Play this glass flute to recover from Sleep status. |
| Blue Orb | A blue, glowing orb said to contain an ancient power. |
| Blue Scarf | When held, raises BEAUTY in contests. |
| Blue Shard | Appears to be a fragment of an item made long ago. Sells low. |
| Bluk Berry | Bury in the earth to grow BLUK ingredients for PokéBlocks. |
| Brightpowder | Hold and a light lowers the opponent's accuracy. |
| Burn Heal | Recover from Burn status. |
| Calcium | Raises Special Attack points. |
| Carbos | Raises Speed points. |
| Charcoal | When held, a Pokemon's Fire type moves' power increases by 10%. |
| Cheri Berry | When held, Paralyze status recovers by itself. |
| Chesto Berry | When held, Sleep status recovers by itself. |
| Choice Band | The attack power of a move becomes times 1.5, but only that move can be used. |
| Claw Fossil | A fossil of an ancient Pokemon believes to live on the sea floor. |
| Cleanse Tag | When held by a Pokemon, wild Pokemon will be encountered less often. |
| Coin Case | A case that holds up to 9,999 COINS. |
| Contest Pass | A pass required to participate in a contest. |
| Cornn Berry | Bury in the earth to grow CORNN ingredients for PokéBlocks. |
| Deepseascale | A scale that doubles Clamperl's SPECIAL DEFENSE when held. |
| Deepseatooth | A fang that doubles Clamperl's SPECIAL ATTACK when held. |
| Devon Goods | A package that contains DEVON's machine parts. |
| Devon Scope | A special item made by Devon. It makes a sound when it finds an unseen Pokemon. |
| Dire Hit | Critical hits occur more often in battle. |
| Dive Ball | A ball that makes it easy to catch Pokemon on the ocean floor. |
| Dragon Fang | When held, a Pokemon's Dragon type moves' power increases by 10%. |
| Dragon Scale | A mysterious scale held by Dragon type Pokemon. |
| Dream Mail | Mail which shows a sketch of the Pokemon holding it. |
| Durin Berry | Bury in the earth to grow DURIN ingredients for PokéBlocks. |
| Elixir | Recovers 10 PP for all moves. |
| Energy Root | A very bitter root which recovers 200 HP for a Pokemon. |
| Energypowder | A very bitter powder which recovers 50 HP for a Pokemon. |
| Enigma Berry | Bury in the earth to grow mysterious ingredients for PokéBlocks. |
| Eon Ticket | The ticket for a ferry to a distant southern island. |
| Escape Rope | Escape from caves and dungeons. |
| Ether | Recovers 10 PP for one move. |
| Everstone | A mysterious rock that prevents a Pokemon from evolving when held. |
| Exp. Share | When held by a Pokemon, its Experience Value and Effort Value raise without battling. |
| Fab Mail | Gorgeous-print mail which a Pokemon holds. |
| Figy Berry | When held, 1/8 HP recovers when HP is below half, but Confusion occurs for Pokemon that are Bold, Timid, Modest, or Calm. |
| Fire Stone | A stone which evolves special Pokemon. |
| Fluffy Tail | Run away from wild Pokemon without fail. |
| Focus Band | When held, sometimes the Pokemon will survive with 1 HP instead of 0 HP. |
| Fresh Water | A mineral-filled water which recovers 50 HP for a Pokemon. |
| Full Heal | Recovers from any status ailment. |
| Full Restore | Pokemon recovers full HP and from any status ailment. |
| Ganlon Berry | When held, while in a pinch, Defense raises one stage. |
| Glitter Mail | Pikachu-print mail which a Pokemon holds. |
| Go-Goggles | Great goggles which protect the eyes from desert sandstorms. |
| Good Rod | A better rod used to fish for Pokemon. |
| Great Ball | Easier to catch than with a Poke Ball. |
| Green Scarf | When held, raises SMART in contests. |
| Green Shard | Appears to be a fragment of an item made long ago. Sells low. |
| Grepa Berry | Bury in the earth to grow GREPA ingredients for PokéBlocks. |
| Guard Spec. | Abilities cannot be lowered in battle. |
| Harbor Mail | Wingull-print mail which a Pokemon holds. |
| Hard Stone | When held, a Pokemon's Rock type moves' power increases by 10%. |
| Heal Powder | An extremely bitter powder which completely recovers from any status ailment. |
| Heart Scale | A beautiful scale which is popular among collectors. |
| Hondew Berry | Bury in the earth to grow HONDEW ingredients for PokéBlocks. |
| HP Up | Raises HP. |
| Hyper Potion | Pokemon recovers 200 HP. |
| Iapapa Berry | When held, 1/8 HP recovers when HP is below half, but Confusion occurs for Pokemon that are Lonely, Hasty, Mild, or Gentle. |
| Ice Heal | Recover from Freeze status. |
| Iron | Raises Defense points. |
| Itemfinder | Makes a sound when an unseen item is detected. |
| Kelpsy Berry | Bury in the earth to grow KELPSY ingredients for PokéBlocks. |
| King's Rock | When held by a Pokemon, its attacks may cause the opponent to flinch. |
| Lansat Berry | When held, while in a pinch, it becomes easy to Critical Hit the enemy. |
| Lava Cookie | A local specialty which completely recovers from any status ailment. |
| Lax Incense | When held, the enemy's accuracy lowers slightly by 5%. |
| Leaf Stone | A stone which evolves special Pokemon. |
| Leftovers | When held, HP recovers by 1/16th every turn. |
| Lemonade | A very sweet which recovers 80 HP for a Pokemon. |
| Leppa Berry | When held, 10 PP recovers by itself when PP is 0. |
| Letter | A letter to STEVEN from the PRESIDENT of the DEVON CORP. |
| Liechi Berry | When held, while in a pinch, Attack raises one stage. |
| Light Ball | A glowing ball that doubles Pikachu's SPECIAL ATTACK when held. |
| Lucky Egg | When held, a Pokemon gains more experience |
| Lucky Punch | When held, it is easier for Chansey to Critical Hit. |
| Lum Berry | When held, any status ailment recovers by itself. |
| Luxury Ball | A caught Pokemon's Tameness Value is higher. |
| Mach Bike | A folding bicycle that more than doubles movement speed. |
| Macho Brace | When held by a Pokemon, Speed lowers one stage, but Effort Values earned doubles. |
| Magnet | When held, a Pokemon's Electric type moves' power increases by 10%. |
| Mago Berry | When held, 1/8 HP recovers when HP is below half, but Confusion occurs for Pokemon that are Brave, Relaxed, Quiet, or Sassy. |
| Magost Berry | Bury in the earth to grow MAGOST ingredients for PokéBlocks. |
| Master Ball | The greatest ball, it catches Pokemon without fail. |
| Max Elixir | Recovers all PP for one Pokemon. |
| Max Ether | Recovers full PP for one move. |
| Max Potion | Pokemon recovers full HP. |
| Max Repel | Do not encounter weaker Pokemon for 250 steps. |
| Max Revive | Recovers from Faint status with full HP recovered. |
| Mech Mail | Magmemite-print mail which a Pokemon holds. |
| Mental Herb | When held, Attract recovers by itself. |
| Metal Coat | When held, a Pokemon's Steel type moves' power increases by 10%. |
| Metal Powder | When held, Ditto's DEFENSE and SPECIAL DEFENSE become times 1.5. |
| Meteorite | A fallen meteorite found in Meteor Falls. |
| Miracle Seed | When held, a Pokemon's Grass type moves' power increases by 10%. |
| Moomoo Milk | A nutrition-filled milk which recovers 100 HP for a Pokemon. |
| Moon Stone | A stone which evolves special Pokemon. |
| Mystic Water | When held, a Pokemon's Water type moves' power increases by 10%. |
| Nanab Berry | Bury in the earth to grow NANAB ingredients for PokéBlocks. |
| Nest Ball | A ball that easily catches Pokemon weaker than your own. |
| Net Ball | A ball that makes it easy to catch Water and Bug type Pokemon. |
| Nevermeltice | When held, a Pokemon's Ice type moves' power increases by 10%. |
| Nomel Berry | Bury in the earth to grow NOMEL ingredients for PokéBlocks. |
| Nugget | A solid gold nugget. Sells high. |
| Old Rod | Use to fish for Pokemon in the water. |
| Oran Berry | When held, 10 HP recovers by itself when HP is below half. |
| Orange Mail | Zigzagoon-print mail which a Pokemon holds. |
| Pamtre Berry | Bury in the earth to grow PAMTRE ingredients for PokéBlocks. |
| Parlyz Heal | Recover from Paralyze status. |
| Pearl | A pretty pearl. Sells low. |
| Pecha Berry | When held, Poison status recovers by itself. |
| Persim Berry | When held, Confusion status recovers by itself. |
| Petaya Berry | When held, while in a pinch, Special Attack raises one stage. |
| Pinap Berry | Bury in the earth to grow PINAP ingredients for PokéBlocks. |
| Pink Scarf | When held, raises CUTE in contests. |
| Poison Barb | When held, a Pokemon's Poison type moves' power increases by 10%. |
| Poké Ball | Item used to catch wild Pokemon. |
| Poké Doll | Run away from wild Pokemon without fail. |
| PokéBlock Case | A case for holding PokéBlocks made with a BERRY BLENDER. |
| Pomeg Berry | Bury in the earth to grow POMEG ingredients for PokéBlocks. |
| Potion | Pokemon recoveres 20 HP. |
| PP Max | PP's maximum raises to its limit. |
| PP Up | PP's maximum raises. |
| Premier Ball | A new, commemorative Poke Ball. |
| Protein | Raises Attack points. |
| Qualot Berry | Bury in the earth to grow QUALOT ingredients for PokéBlocks. |
| Quick Claw | When held by a Pokemon, a preemptive attack may occur. |
| Rabuta Berry | Bury in the earth to grow RABUTA ingredients for PokéBlocks. |
| Rare Candy | Pokemon raises 1 level. |
| Rawst Berry | When held, Burn status recovers by itself. |
| Razz Berry | Bury in the earth to grow RAZZ ingredients for PokéBlocks. |
| Red Flute | Play this glass flute to recover from Attract status. |
| Red Orb | A red, glowing orb said to contain an ancient power. |
| Red Scarf | When held, raises COOL in contests. |
| Red Shard | Appears to be a fragment of an item made long ago. Sells low. |
| Repeat Ball | Pokemon already caught are easier to catch. |
| Repel | Do not encounter weaker Pokemon for 100 steps. |
| Retro Mail | Three starter Pokemon-print mail which a Pokemon holds. |
| Revival Herb | A very bitter herb which recovers from Faint status. |
| Revive | Recovers from Faint status with half HP recovered. |
| Rm. 1 Key | A key that opens a door inside the ABANDONED SHIP. |
| Rm. 2 Key | A key that opens a door inside the ABANDONED SHIP. |
| Rm. 4 Key | A key that opens a door inside the ABANDONED SHIP. |
| Rm. 6 Key | A key that opens a door inside the ABANDONED SHIP. |
| Root Fossil | A fossil of an ancient Pokemon believes to live on the sea floor. |
| S.S. Ticket | A ticket required to sail on a ferry. |
| Sacred Ash | Revives all Pokemon from Faint status. |
| Safari Ball | A special ball made to use only in the Safari Zone. |
| Salac Berry | When held, while in a pinch, Speed raises one stage. |
| Scanner | A device found inside the ABANDONED SHIP. |
| Scope Lens | When held, it is easier for a Pokemon to Critical Hit. |
| Sea Incense | When held, a Pokemon's Water type moves' power increases slightly by 5%. |
| Shadow Mail | Duskull-print mail which a Pokemon holds. |
| Sharp Beak | When held, a Pokemon's Flying type moves' power increases by 10%. |
| Shell Bell | When held, a Pokemon recovers HP equal to 1/8th the damage its attacks deal to the opponent. |
| Shoal Salt | Salt obtained from deep inside the SHOAL CAVE. |
| Shoal Shell | A seashell found deep inside the SHOAL CAVE. |
| Silk Scarf | When held, a Pokemon's Normal type moves' power increases by 10%. |
| Silverpowder | When held, a Pokemon's Bug type moves' power increases by 10%. |
| Sitrus Berry | When held, 30 HP recovers by itself when HP is below half. |
| Smoke Ball | Run away from wild Pokemon without fail. |
| Soda Pop | A fizzy soda which recovers 60 HP for a Pokemon. |
| Soft Sand | When held, a Pokemon's Ground type moves' power increases by 10%. |
| Soot Sack | A sack used to gather and hold volcanic ash. |
| Soothe Bell | When held, a Pokemon's Tameness Value raises more easily. |
| Soul Dew | When held, Latias or Latios's SPECIAL ATTACK and SPECIAL DEFENSE raise. |
| Spell Tag | When held, a Pokemon's Ghost type moves' power increases by 10%. |
| Spelon Berry | Bury in the earth to grow SPELON ingredients for PokéBlocks. |
| Star Piece | A red gem shard. Sells very high. |
| Stardust | Beautiful red sand. Sells high. |
| Starf Berry | When held, while in a pinch, one ability raises two stages. |
| Stick | When held, it is easier for Farfetch'd to Critical Hit. |
| Storage Key | The key to the storage inside the ABANDONED SHIP. |
| Sun Stone | A stone which evolves special Pokemon. |
| Super Potion | Pokemon recovers 50 HP. |
| Super Repel | Do not encounter weaker Pokemon for 200 steps. |
| Super Rod | The best rod used to fish for Pokemon. |
| Tamato Berry | Bury in the earth to grow TAMATO ingredients for PokéBlocks. |
| Thick Club | When held, Cubone and Marowak's ATTACK becomes times 2. |
| Thunderstone | A stone which evolves special Pokemon. |
| Timer Ball | After a number of turns that go by, it becomes easier to catch a Pokemon. |
| Tinymushroom | A plain, ordinary mushroom. Sells low. |
| Tropic Mail | Bellossom-print mail which a Pokemon holds. |
| Twistedspoon | When held, a Pokemon's Psychic type moves' power increases by 10%. |
| Ultra Ball | Easier to catch than with a Great Ball. |
| Up-Grade | When held, evolves Porygon when traded. |
| Wailmer Pail | Used to pour water on the ground. Buried trees will quickly grow berries. |
| Water Stone | A stone which evolves special Pokemon. |
| Watmel Berry | Bury in the earth to grow WATMEL ingredients for PokéBlocks. |
| Wave Mail | Wailmer-print mail which a Pokemon holds. |
| Wepear Berry | Bury in the earth to grow WEPEAR ingredients for PokéBlocks. |
| White Flute | Play this glass flute to encounter wild Pokemon more often. |
| White Herb | When held by a Pokemon, if an ability is lowered, it will be raised back up. |
| Wiki Berry | When held, 1/8 HP recovers when HP is below half, but Confusion occurs for Pokemon that are Adamant, Impish, Jolly, or Careful. |
| Wood Mail | Slakoth print mail which a Pokemon holds. |
| X Accuracy | Accuracy raises in battle. |
| X Attack | ATTACK power raises in battle. |
| X Defend | DEFENSE power raises in battle. |
| X Special | SPECIAL ATTACK's power raises in battle. |
| X Speed | SPEED raises in battle. |
| Yellow Flute | Play this glass flute to recover from Confusion status. |
| Yellow Scarf | When held, raises TOUGH in contests. |
| Yellow Shard | Appears to be a fragment of an item made long ago. Sells low. |
| Zinc | Raises Special Defense points. |